团队围绕优异基因挖掘、育种平台构建和新品种选育等研究方向，针对水稻种业发展的前沿科学问题，主要开展水稻抗逆抗病虫优异基因挖掘与分子功能解析、分子设计育种平台构建和高产优质多抗绿色超级稻新品种培育工作。克隆水稻抗白叶枯病、抗二化螟、抗稻纵卷叶螟、抗条纹叶枯病、抗旱、耐盐、耐热、穗粒数等基因，构建了全基因组选择预测软件/模型MFMGP、水稻智能育种平台“Rice3kGS”和基于影响穗颈节维管束相关性状的产量和外观品质相关基因同步提高粳稻产量和品质的分子设计育种策略，相关研究成果在Molecular Plant、Science Bulletin、Plant Biotechnology Journal、Plant Communications、Journal of Integrative Plant Biology、Plant Journal等期刊发表SCI论文29篇，授权国家发明专利7项、植物新品种保护权4项、审定品种13个（其中国审5个），成果转化收入486万元。
1. 代表性论文
(1) Mingyue Huo, Shanwen Wang, Fan Zhang, Min Li, Ming Yin, Yuxin Lei, Yanfang Wang, Yanjun Chen, Dapu Liu, Xiuqin Zhao, Binying Fu, Fengyi Hu, Jianlong Xu, Zhikang Li, Wensheng Wang. Strong tri-genic epistasis among natural alleles of module OsMYB2-OsGH18-OsCAD3 confers improved drought tolerance in rice. Molecular Plant (2026), DOI:10.1016/j.molp.2026.01.005.
(2) Min Ning, Qinyan Li, Ya Wang, Qingmao Li, Yonghong Tao, Fan Zhang, Fengyi Hua, Liyu Huang. Alternative splicing drives the functional diversification of a bHLH transcription factor in the control of growth and drought tolerance in rice. Science Bulletin (2025), 70: 153–156. DOI:10.1016/j.scib.2024.06.001.
(3) Chaopu Zhang, Qiqi Liang, Yuye Yu, Shaojuan Jin, Jinmei Huang, Zhongping Xu , Erbao Liu, Wensheng Wang, Fan Zhang, Fangzhou Liu, Yingyao Shi, Fenge Li, Zhikang Li, Shuangxia Jin, Min Li. MFMGP: an integrated machine learning fusion model for genomic prediction. Plant Biotechnology Journal (2025), 23: 712–714. DOI:10.1111/pbi.14532.
(4) Chaopu Zhang, Yanru Cui, Cong Yuan, Fan Zhang, Qian Zhu, Shijiao Li, Shuyue Zheng, Shuran Zhou, Tingting Sheng, Xianjin Qiu, Qiqi Liang, Yuye Yu, Wensheng Wang, Min Li. Rice3KGS: A powerful web platform and database for large-scale genome selection. Plant Communications (2025), 6(8):101369. DOI:10.1016/j.xplc.2025.101369.
(5) Bo Zhao, Guojuan Xu, Yajun Zhu, Hui Zhang, Yuanbo Zhang, Chunxue Wei, Xi Chen, Zhichao Wu,Ruifang Liu, Kai Chen, Congcong Shen, Ling Ding, Xu Wang, Wenhui Jiang, Wangang An, Lei Ren, Zhan Xu, Jianlong Xu and Yong Xiang. A six-repeat PPR protein WPR directly binds target RNAs and coordinates chloroplast RNA processing via dual recruitment of MORF1, MORF8b, and CAF2 proteins in rice. The Plant Journal (2025), 124: e70526. DOI:10.1111/tpj.70526.
(6) Ming Yin, Mingyue Huo, Shanwen Wang, Yong Zhao, Yuxin Lei, Xiaoyu Chu, Liying Zuo, Yawei Liang,Dapu Liu, Xiuqin Zhao, Fan Zhang, Binying Fu, Zichao Li , Zhikang Li, Jianlong Xu and Wensheng Wang. Multi-Omics insights into OsZFP252-OsGA20ox5 mediated drought tolerance in rice through stomatal and vascular regulation. The Plant Journal (2025), 124: e70497. DOI: 10.1111/tpj.70497.
(7) Lunping Liang, Chaopu Zhang, Linjun Yu, Tingting Sheng, Shuyue Zheng, Shijiao Li , Shuran Zhou , Ting Feng, Fan Zhang, Zhikang Li, Yanru Cui , Wensheng Wang , Min Li. Comprehensive comparison between structural variants and single nucleotide polymorphism in genomic selection of rice (Oryza sativa L.). The Crop Journal (2025), 13(6): 1962–1967. DOI:10.1016/j.cj.2025.08.005.
(8) Muhammad Sohaib Shafique, Yapei Liu, Man Li, Hongjie Wang, Ruyi Su, Chunlian Wang, Zhiyuan Ji, Coevolution unveiled: Sulfate transporters mediate rice resistance and susceptibility to Xanthomonas oryzae pv. oryzicola. Plant Biotechnology Journal (2024), 22(9): 2632–2634. DOI:10.1111/pbi.14377.
(9) Ding Ren, Hui Liu, Xuejun Sun, Fan Zhang, Ling Jiang, Ying Wang, Ning Jiang, Peiwen Yan, Jinhao Cui, Jinshui Yang, Zhikang Li, Pingli Lu, Xiaojin Luo. Post-transcriptional regulation of grain weight and shape by the RBP-A-J-K complex in rice. Journal of Integrative Plant Biology (2024), 66: 66–85. DOI:10.1111/jipb.13583.
(10) Yun Wang, Xiaoqian Wang, Laiyuan Zhai, Sundu Zafar, Congcong Shen, Shuangbing Zhu, Kai Chen, Wang Yun, Jianlong Xu. A novel Effective Panicle Number per Plant 4 haplotype enhances grain yield by coordinating panicle number and grain number in rice. The Crop Journal (2024), 12(1): 202–212. DOI:10.1016/j.cj.2023.11.003.
2. 代表性专利、软著与专著
(1) LOC_Os12g07640基因及其编码蛋白在提高植物抗干旱胁迫中的用途，王文生、霍明月、尹明、雷雨鑫、张帆、赵秀琴、傅彬英、徐建龙，ZL202411587216.2；
(2) 水稻OsWRKY15基因及其编码蛋白在调控植物抗干旱胁迫中的用途，王文生、雷雨鑫、霍明月、杜丰平、左丽英、刘大普、张帆、赵秀琴、傅彬英、徐建龙，ZL202510258244.8；
(3) 水稻抗白叶枯病相关蛋白XA50及其编码基因与应用，纪志远、李曼、刘亚培、王春连，ZL2022510220404.X；
(4) 水稻Lhca4基因及其编码蛋白在提高植物抗盐胁迫中的用途，赵秀琴、张帆、钱玉康、谢自艳、郑天清、徐建龙、王文生，ZL202411587218.1；
(5) 水稻Os05g0498700蛋白及其编码基因在提高植物抗非生物胁迫中的用途，王文生、尹明、张岳、郑珍珍、张帆、赵秀琴、傅彬英、徐建龙，ZL202410618897.8.
3. 重要品种
(1) 中农粳11，黑审稻2024L0028，佳木斯恒新农业技术科研所、中国农业科学院作物科学研究所;
(2) 荃优93，国审稻20244009，中国农业科学院作物科学研究所；中国农业科学院深圳农业基因组研究所（岭南现代农业科学与技术广东省实验室深圳分中心）；安徽荃银高科种业股份有限公司;
(3) 春9两优16，国审稻20243001，中国农业科学院作物科学研究所、中国农业科学院深圳农业基因组研究所、广东省农业科学院水稻研究所;
(4) 中农粳186，黑审稻20250029，中国农业科学院作物科学研究所、黑龙江田友种业有限公司;
(5) 中农粳508，黑审稻2025L0081，黑龙江省莲江口种子有限公司，中国农业科学院作物科学研究所。
4. 科技成果奖励
(1) 亚洲栽培稻遗传多样性解析与利用, 中国农业科学院青年科技创新奖，王文生，张帆，郑天清，黎珉，徐建龙，黎志康，傅彬英，赵秀琴，陈凯，高用明，申聪聪，张超普，2025年。
