团队针对重大新品种培育对关键基因资源的迫切需求，利用小麦自然群体、核心种质及突变体材料，系统解析产量、品质和抗逆等重要农艺性状的遗传基础和分子调控网络，揭示小麦品种选育及驯化过程中基因组演变规律。在此基础上，通过集成规模化基因发掘、基因编辑和调控元件精准设计等技术，挖掘关键优异基因并创制育种新材料，支撑小麦品种改良。团队承担了国家重点研发计划、农业生物育种重大项目、国家自然科学基金等多个国家级项目，在小麦基因组演化、重要基因克隆与功能解析等方面取得了一批代表性成果，相关研究发表在Nature、Nature Plants、Nature Communications和Plant Cell等国际知名期刊，创制了一批优异新材料，育成中麦69和中麦678等多个高产广适国审新品种。
1. 代表性论文
(1) Chengzhi Jiao, Xiaoming Xie, Chenyang Hao, Liyang Chen, Yuxin Xie, Vanika Garg, Li Zhao, Zihao Wang, Yuqi Zhang, Tian Li, Junjie Fu, Annapurna Chitikineni, Jian Hou, Hongxia Liu, Girish Dwivedi, Xu Liu, Jizeng Jia, Long Mao, Xiue Wang, Rudi Appels, Rajeev K. Varshney, Weilong Guo, Xueyong Zhang. Pan-genome bridges wheat structural variations with habitat and breeding. Nature (2025), 637(8045):384-393.
(2) Chunhao Dong, Lichao Zhang, Qiang Zhang, Yuxin Yang, Danping Li, Zhencheng Xie, Guoqing Cui, Yaoyu Chen, Lifen Wu, Zhan Li, Guoxiang Liu, Xueying Zhang, Cuimei Liu, Jinfang Chu, Guangyao Zhao, Chuan Xia, Jizeng Jia, Jiaqiang Sun, Xiuying Kong, Xu Liu. Tiller Number1 encodes an ankyrin repeat protein that controls tillering in bread wheat. Nature Communications (2023), 14(1):836.
(3) Yuange Wang, Bofei Cui, Fei Du, Jian Li, Yuling Jiao. Grass inflorescence morphodynamics guides yield improvement in wheat. Nature Plants (2026), in press.
(4) Yunchuan Liu, Mingming Wang, Yaojia Wang, Haixia Liu, Wei Xi, David Seung, Xiaolu Wang, Lei Zhuang, Huifang Li, Tian Li, Hongxia Liu, Jian Hou, Xu Liu, Chenyang Hao, Xueyong Zhang. The transcription factor MYB44 suppresses starch synthesis to negatively regulate grain weight and yield in wheat and rice. Molecular Plant (2025), 18(7):1193-1209.
(5) Huixue Dong, Danping Li, Ruizhen Yang, Lichao Zhang, Yunwei Zhang, Xu Liu, Xiuying Kong, Jiaqiang Sun. GSK3 phosphorylates and regulates the Green Revolution protein Rht-B1b to reduce plant height in wheat. Plant Cell (2023), 35(6):1970-1983.
(6) Pan Liu, Shulin Xue, Jizeng Jia, Guangyao Zhao, Jie Liu, Yanzhen Hu, Cuizheng Kong, Dong Yan, Huan Wang, Xu Liu, Zefu Lu, Lifeng Gao. The wheat transcription factor Q functions in gibberellin biosynthesis and signaling and regulates height and spike length. Plant Cell (2025). 37(8):koaf183.
(7) Zhigang Ma, Jiazi Zhang, Hongcui Pei, Yanhong Liu, Hongning Tong, Lei Wang, Zefu Lu. DeepWheat: predicting the effects of genomic variants on gene expression and regulatory activities across tissues and varieties in wheat using deep learning. Genome Biology (2025), 26(1):321.
(8) Yinhui Zhang, Haixia Liu, Yaojia Wang, Xuemei Si, Yuxue Pan, Mengjiao Guo, Meijuan Wu, Yuanhao Li, Hongxia Liu, Xueyong Zhang, Jian Hou, Tian Li, Chenyang Hao. TaFT-D1 positively regulates grain weight by acting as a coactivator of TaFDL2 in wheat. Plant Biotechnology Journal (2025), 23(6):2207-2223.
(9) Yaoyu Chen, Zhe Yang, Huanhuan Wang, Chuan Xia, Lichao Zhang, Jiaqiang Sun, Xiuying Kong, Xu Liu. Two open reading frames of Rht-B1b acting as brake and throttle contributed to wheat Green Revolution. Plant Physiology (2024), 194(3):1290-1293.
(10) Zipei Fan, Xiaosha Tang, Jingyi Wang, Yang Zhao, Wenjing An, Yujing Jia, Zhixiong Pan, Yao Wang, Long Li, Xinguo Mao, Daizhen Sun, Jiemeng Xu, Matthew Paul Reynolds, Ruilian Jing, Chaonan Li. The drought-responsive bHLH gene TaMIP1 controls root density to confer the trade-off between grain yield and drought resistance in wheat. Plant Physiology (2026), in press.
2. 代表性专利、软著与专著
(1) 检测或辅助检测小麦穗粒数的物质及其应用，郝晨阳、张寅辉、刘红霞、侯健、李甜、张学勇，ZL202411661656.8；
(2) 检测或辅助检测小麦株高的物质及其应用，郝晨阳、张寅辉、刘红霞、侯健、李甜、张学勇，ZL202411680945.2。
3. 重要品种
(1) 中麦69，国审麦20230133，中国农业科学院作物科学研究所；
(2) 中麦678，国审麦20253085，中国农业科学院作物科学研究所；
(3) 中麦99，豫审麦20241012，中国农业科学院作物科学研究所。
4. 科技成果奖励
(1) 小麦种质资源重要基因多样性发掘与应用，中国农业科学院科学技术成果奖杰出科技创新奖，张学勇、郝晨阳、侯健、董玉琛、贾继增、王兰芬、李甜、刘红霞、刘旭、曹永生、刘三才、姜奇彦、游光霞，2024年。
